Waters ACQUITY UPLC System with PDA Detector, SM, BSM, CM, and Empower 3 Software

Insights by AMPTIUS | AMP Tech Instruments

Ultra-High Performance Liquid Chromatography for Advanced Analytical Laboratories

If your laboratory is looking to accelerate analytical runtime and maximize regulatory compliance data precision during high-resolution separation applications, the Waters ACQUITY UPLC System equipped with a Photodiode Array (PDA) Detector, Sample Manager (SM), Binary Solvent Manager (BSM), Column Manager (CM), and Empower 3 Software delivers the ultimate intelligent, automated solution. Featuring a high-pressure Binary Solvent Manager capable of delivering precise gradients at up to 15,000 psi, the high-performance platform works alongside sub-2 µm particle columns to guarantee flawless chromatographic efficiency and exceptional peak capacity across a wide range of analytical applications. The integrated Column Manager and PDA Detector further streamline your workflow by automating thermostatted column selection and acquiring full UV-Visible spectra simultaneously, completely removing system dispersion and manual method development restrictions prior to data reporting. It is a premier, robust powerhouse for environmental facilities tracking regulated contaminants, as well as pharmaceutical operations requiring uncompromised reproducibility and data integrity for strict API analysis, dissolution testing, impurity profiling, and stability studies.

Waters ACQUITY UPLC System with PDA Detector Price and Cost of Ownership: Reliable Performance at Lower Cost

The total cost of ownership for the Waters ACQUITY UPLC System with a PDA Detector, Sample Manager (SM), Binary Solvent Manager (BSM), Column Manager (CM), and Empower 3 Software includes the initial acquisition cost as well as ongoing expenses for preventive maintenance, pump seal and check valve replacement, autosampler servicing, PDA lamp replacement, column maintenance, software support, and routine system calibration. A certified refurbished Waters ACQUITY UPLC System typically ranges from $22,000 to $35,000, providing significant savings compared to a new Waters ACQUITY Premier UPLC System with a PDA Detector and Empower 3 Software, which generally costs between $110,000 and $145,000. For laboratories seeking high-performance UPLC capabilities without the substantial capital investment of a new platform, a professionally refurbished system offers exceptional value by delivering reliable ultra-high-pressure separations, advanced PDA detection, automated sample handling, and trusted Empower 3 data management. When purchased from a reputable supplier with comprehensive testing, certification, and warranty coverage, a refurbished Waters ACQUITY UPLC System provides a cost-effective solution that maintains the performance, reliability, and regulatory compliance required for routine quality control, method development, and analytical laboratory workflows.

Pharmaceutical Quality Control (QC) and Generic Drug Manufacturing Using the Waters ACQUITY UPLC System with PDA Detector

The Waters ACQUITY UPLC System with a PDA Detector, Sample Manager (SM), Binary Solvent Manager (BSM), Column Manager (CM), and Empower 3 Software is an ideal platform for pharmaceutical quality control (QC) and generic drug manufacturing, delivering the speed, precision, and regulatory compliance required for routine analytical testing. The system provides high-resolution separations for active pharmaceutical ingredient (API) assays, impurity profiling, dissolution testing, content uniformity, stability studies, and method validation, while the PDA Detector enables full-spectrum analysis for accurate peak identification, peak purity assessment, and reliable quantitation. The Binary Solvent Manager ensures precise gradient formation, the Sample Manager provides reproducible automated sample injection, and the Column Manager maintains consistent temperature control for enhanced chromatographic reproducibility. Empower 3 Software streamlines data acquisition, processing, audit trails, and electronic records to support compliance with FDA 21 CFR Part 11 and global regulatory requirements. Combined with exceptional analytical performance, high-throughput capabilities, and proven Waters reliability, the Waters ACQUITY UPLC System provides a robust solution for pharmaceutical QC laboratories and generic drug manufacturers seeking efficient, accurate, and compliant analytical workflows.

AMP Tech Analytical Solutions for Academic Research and Grant-Funded Laboratories

At AMPTIUS | AMP Tech Instruments, we support the advancement of scientific education and innovation by providing cost-effective analytical instruments tailored to the unique budget constraints of the academic sector. Every pre-owned system in our inventory is independently evaluated and fully verified within our in-house testing laboratory, making our AMP Tech Certified equipment an ideal choice for university chemistry departments, core facilities, and researchers optimizing limited grant funding. Because academic applications vary heavily from undergraduate teaching labs to complex graduate research, we precisely document each unique listing to ensure the specific components align with your educational goals or specific institutional SOPs. To guarantee that your system includes the exact module configuration required for your research methodology and to align with your university’s procurement process or funding timeline, we highly encourage you to connect directly with our active sales management team or request a customized quote before purchase.