Agilent 1290 Infinity II UHPLC System with DAD Detector

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Agilent 1290 Infinity II UHPLC System with DAD Detector: Applications in Pharma, Food, and Environmental Labs

The Agilent 1290 Infinity II UHPLC System with Diode Array Detection (DAD) is widely used for ultra-high-performance chromatographic analysis in pharmaceutical, environmental, food safety, biotechnology, chemical, academic, and industrial laboratories. Common laboratory applications include pharmaceutical assay testing, impurity profiling, dissolution studies, stability-indicating methods, and raw material verification in workflows aligned with USP <621>, FDA, ICH, and cGMP analytical requirements. Environmental laboratories commonly utilize the system for pesticide analysis, organic contaminant monitoring, carbonyl compound testing, and polynuclear aromatic hydrocarbon (PAH) analysis following EPA methods such as EPA 8315A and EPA 8330B. In food safety laboratories, the configuration supports preservative analysis, additive testing, mycotoxin screening, beverage quality analysis, and nutritional compound quantitation following AOAC analytical frameworks. Biotechnology and research laboratories frequently apply the system for peptide analysis, biomolecule characterization, metabolite profiling, and reaction monitoring workflows. The DAD enables simultaneous multi-wavelength monitoring and full spectral acquisition for enhanced compound identification and peak purity analysis, while the Agilent 1290 Infinity II UHPLC platform delivers ultra-high-pressure solvent delivery, fast gradient separations, low carryover, stable retention times, and exceptional chromatographic reproducibility for routine and high-throughput laboratory applications.

Agilent 1290 Infinity II UHPLC with DAD: Refurbished System Benefits and Pricing

The Agilent 1290 Infinity II UHPLC System with Diode Array Detection (DAD) provides a premium ultra-high-performance chromatography solution for pharmaceutical, environmental, food safety, biotechnology, and research laboratories requiring fast separations and high-resolution analytical performance. New systems typically range from approximately $90,000 to over $120,000, depending on detector configuration, autosampler options, software packages, and module selection, while certified refurbished systems generally range from $45,000 to $68,000, offering substantial savings on initial capital investment. In addition to acquisition costs, laboratories should consider ongoing operational expenses such as UHPLC solvents, mobile phase additives, high-pressure analytical columns, DAD lamp replacements, tubing, pump seals, autosampler consumables, calibration standards, preventive maintenance, software licensing, and compliance-related qualification support for USP, FDA, ICH, EPA, AOAC, ISO, and cGMP workflows. Long-term ownership considerations may also include detector servicing, pump maintenance, replacement electronic components, and optional service contracts to maintain ultra-high-pressure system performance and dependable chromatographic reproducibility in high-throughput laboratory environments. Purchasing a certified refurbished Agilent 1290 Infinity II UHPLC System with DAD Detector allows laboratories to significantly reduce ownership costs while still benefiting from fast gradient separations, reliable multi-wavelength detection, exceptional chromatographic resolution, and proven long-term analytical performance for regulated and research-based applications.

EPA Method 555: Determination of Chlorinated Acids in Water Using Agilent 1290 Infinity II UHPLC System with DAD Detector

The Agilent 1290 Infinity II UHPLC System with Diode Array Detection (DAD) provides a highly efficient and reliable platform for laboratories performing EPA Method 555 for the determination of chlorinated acids in drinking water and environmental samples. This UHPLC configuration delivers exceptional chromatographic resolution, rapid gradient separations, and precise retention time reproducibility for chlorinated herbicides and related acidic compounds commonly analyzed in regulated water testing workflows. The integrated DAD enables simultaneous multi-wavelength monitoring and full spectral acquisition, supporting enhanced analyte confirmation, peak purity analysis, and improved identification of target compounds in complex water matrices. The Agilent 1290 Infinity II platform also offers ultra-high-pressure solvent delivery, low carryover, stable baseline performance, and dependable quantitative accuracy, making it well-suited for high-throughput environmental laboratories requiring reliable trace-level contaminant analysis. Combined with automated workflow capabilities, strong chromatographic reproducibility, and dependable long-term operation, the Agilent 1290 Infinity II UHPLC System with DAD Detector provides laboratories with excellent sensitivity, analytical confidence, and operational reliability for EPA Method 555 applications.