Agilent 6410A Triple Quad LC/MS System with 1100 HPLC - Tested and certified

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Price and cost of ownership of Agilent 6410A Triple Quad LC/MS System with 1100 HPLC - Tested and certified

The Agilent 6410A Triple Quadrupole LC/MS System paired with the 1100 HPLC is a robust analytical solution designed for high-sensitivity quantitative analysis across pharmaceutical, environmental, and food testing laboratories. A new system is priced around $260,000, while a certified refurbished unit is available for approximately $50,000, representing a substantial reduction in acquisition cost—nearly 80% savings. This system combines the 6410A triple quadrupole mass spectrometer, known for its precise and reproducible quantitation, with the proven performance of the Agilent 1100 HPLC, which includes reliable binary pumping, autosampling, and diode-array detection. Together, they offer efficient chromatographic separation and accurate mass detection in a fully integrated platform. Though upfront costs are sharply reduced when purchasing refurbished, long-term ownership still involves regular expenditures on LC columns, solvents, source maintenance (e.g., ion optics and capillaries), pump seals, and potential repairs of key components like the vacuum system or RF electronics. Software licensing and compliance-related updates may also apply in regulated environments. Choosing a tested and certified refurbished 6410A system is a practical option for labs aiming to expand LC-MS/MS capabilities without the financial burden of a new instrument—delivering high performance and reliability at a fraction of the cost.

High-Performance LC/MS System for CDC, WHO, EPA, FDA, and ICH Analytical Method Compliance

The Agilent 6410A Triple Quadrupole LC/MS System with 1100 HPLC is designed for precise quantification of trace compounds in complex samples. It is commonly used in pharmaceutical, food safety, environmental, and forensic labs for applications such as drug analysis, contaminant detection, and toxicology screening. Its triple quad design offers high sensitivity and selectivity, while the 1100 HPLC ensures reliable and reproducible separation for accurate results. The Agilent 6410A Triple Quad LC/MS System with 1100 HPLC is well-suited for a wide range of validated analytical methods that require high sensitivity, precision, and selectivity in quantifying trace-level compounds. It meets the stringent performance requirements of EPA Method 1694, which targets pharmaceuticals and personal care products in water matrices using LC-MS/MS. This system is also compatible with CDC- and WHO-aligned biomonitoring and toxicology screening protocols for measuring environmental and biological contaminants. In pharmaceutical and clinical laboratories, it supports bioanalytical workflows under the FDA Bioanalytical Method Validation Guidance (2022) and ICH Q2(R1), ensuring accurate, precise, and reproducible quantification of drugs and metabolites. Additionally, it performs effectively in food safety applications aligned with AOAC 2007.01, enabling multi-residue pesticide analysis in produce and other agricultural products. Its integrated HPLC and triple quadrupole MS design offers robust and reliable performance across these regulatory frameworks.