Waters ACQUITY UPLC System with Binary Solvent Manager (BSM), Sample Manager (SM), and FLR Detector

Insights by AMPTIUS | AMP Tech Instruments

Ultra-High Performance Fluorescence Chromatography for Advanced Analytical Laboratories

If your laboratory is looking to accelerate analytical runtime and maximize trace-level sensitivity during high-resolution separation applications, the Waters ACQUITY UPLC System equipped with a Binary Solvent Manager (BSM), Sample Manager (SM), and Fluorescence (FLR) Detector delivers the ultimate intelligent, automated solution. Featuring a high-pressure Binary Solvent Manager capable of delivering precise gradients at up to 15,000 psi, the high-performance system works alongside sub-2 µm particle columns to guarantee flawless chromatographic resolution and exceptional peak capacity across a wide range of analytical applications. The integrated Sample Manager and programmable FLR Detector further streamline your workflow by automating temperature-controlled injections and ultra-sensitive fluorescence detection, completely removing sample carryover and dispersion restrictions prior to trace-level data reporting. It is a premier, robust powerhouse for food and beverage facilities tracking aflatoxins, vitamins, and amino acids, as well as pharmaceutical operations requiring uncompromised reproducibility and data integrity for strict impurity profiling and stability studies.

Waters ACQUITY UPLC System with BSM, SM, and FLR Detector Price and Cost of Ownership: Reliable Performance at Lower Cost

The cost of ownership for the Waters ACQUITY UPLC System with Binary Solvent Manager (BSM) and Fluorescence (FLR) Detector offers laboratories an exceptional balance of high-performance chromatography, analytical sensitivity, and long-term value. A comparable new platform, such as the Waters ACQUITY UPLC I-Class PLUS System with Binary Pump, Sample Manager–Flow Through Needle (SM-FTN), and FLR Detector, typically ranges from approximately $115,000 to $140,000, representing a significant capital investment for laboratories requiring advanced UPLC capabilities. In contrast, a certified refurbished Waters ACQUITY UPLC System with BSM and FLR Detector is commonly available between $16,500 and $35,000, providing substantial upfront savings while delivering reliable ultra-performance liquid chromatography for pharmaceutical, biotechnology, environmental, food safety, and research applications. Long-term operational expenses generally include UPLC columns, mobile phase solvents, injector seals, sample loop components, pump seals, check valves, inlet filters, tubing, FLR lamp replacements, preventive maintenance, and periodic servicing to maintain optimal chromatographic performance and instrument uptime. The ACQUITY platform's low-dispersion fluidics, high-pressure capability, and modular architecture help maximize separation efficiency, reduce solvent consumption, and simplify maintenance, contributing to lower lifecycle costs and improved laboratory productivity. Investing in a certified refurbished Waters ACQUITY UPLC System with BSM and FLR Detector further enhances return on investment by providing professionally tested, performance-verified instrumentation at a fraction of the cost of a new ACQUITY UPLC I-Class PLUS system, making it an ideal solution for laboratories seeking dependable, high-resolution UPLC performance while optimizing capital expenditures.

Aflatoxin M1 Determination in Milk Using the Waters ACQUITY UPLC System with BSM, SM, and FLR Detector

The Waters ACQUITY UPLC System with Binary Solvent Manager (BSM), Sample Manager (SM), and Fluorescence (FLR) Detector provides a well-suited platform for the determination of Aflatoxin M1 (AFM1) in milk and dairy products following immunoaffinity column (IAC) cleanup, consistent with AOAC official methodology. AFM1 exhibits strong natural fluorescence, allowing direct quantitation by the ACQUITY FLR Detector without the post-column derivatization required for other aflatoxins such as B1 and G1. The Binary Solvent Manager delivers the precise, reproducible mobile phase delivery needed for isocratic or gradient separation of AFM1 from co-extracted matrix components, while the Sample Manager provides low-carryover, automated injection for consistent performance across extended sample sequences. This configuration is well suited for food safety, dairy quality control, and regulatory testing laboratories performing aflatoxin M1 screening and confirmation.

AMP Tech Analytical Solutions for Academic Research and Grant-Funded Laboratories

At AMPTIUS | AMP Tech Instruments, we support the advancement of scientific education and innovation by providing cost-effective analytical instruments tailored to the unique budget constraints of the academic sector. Every pre-owned system in our inventory is independently evaluated and fully verified within our in-house testing laboratory, making our AMP Tech Certified equipment an ideal choice for university chemistry departments, core facilities, and researchers optimizing limited grant funding. Because academic applications vary heavily from undergraduate teaching labs to complex graduate research, we precisely document each unique listing to ensure the specific components align with your educational goals or specific institutional SOPs. To guarantee that your system includes the exact module configuration required for your research methodology and to align with your university’s procurement process or funding timeline, we highly encourage you to connect directly with our active sales management team or request a customized quote before purchase.