Waters Alliance 2695 HPLC System with Waters 2414 Refractive Index Detector

Insights by AMPTIUS | AMP Tech Instruments

Waters HPLC RID System: Universal Detection for Non-UV Active Compound Analysis

The Waters Alliance 2695 HPLC System, paired with the highly stable Waters 2414 Refractive Index (RI) Detector, is a premier liquid chromatography platform engineered for the precise identification and everyday quantitative analysis of compounds with limited or no UV absorbance. Driven by the smooth, fluidic solvent management and precise automated sample handling of the Alliance 2695 separations module, this system combines excellent retention time reproducibility with an advanced, thermally regulated optical cell. This versatile setup gives labs a truly universal detection solution, keeping baselines perfectly stable while easily measuring sugars, carbohydrates, alcohols, polymers, and lipids that are invisible to standard UV detectors. Thanks to its rugged fluidics and highly sensitive temperature control, the system handles complex, non-chromophoric sample matrices effortlessly, making it a reliable asset for high-throughput testing and everyday regulatory compliance. It serves as an indispensable tool for pharmaceutical and biotech labs managing excipient analysis, formulation testing, and fermentation monitoring, while delivering the exceptional baseline stability and day-to-day reliability required by food safety, beverage, and chemical manufacturing labs for routine nutritional sugar profiling, surfactant characterization, and strict raw material QA/QC workflows.

Waters Alliance 2695 HPLC System Price and Cost of Ownership: Reliable Performance at Lower Cost

The Waters Alliance 2695 HPLC System with Waters 2414 Refractive Index Detector provides a dependable and economical chromatography solution for laboratories performing carbohydrate analysis, polymer testing, food additive analysis, pharmaceutical formulations, and general compound quantitation in pharmaceutical, food safety, chemical, and industrial environments. Certified refurbished systems typically range from approximately $7,450 to $15,500, offering substantial savings compared to newer comparable platforms such as the Waters Alliance iDS HPLC System with Waters 2414 Refractive Index Detector, which commonly range from $62,000 to over $79,000 depending on system configuration and software options. In addition to the initial acquisition cost, laboratories should consider ongoing operational expenses such as HPLC solvents, analytical columns, pump seals, tubing, degasser maintenance, autosampler consumables, detector maintenance, calibration standards, software licensing, preventive maintenance, and compliance-related qualification support for USP, FDA, AOAC, ISO, and cGMP workflows. Long-term ownership considerations may also include refractive index detector temperature stabilization maintenance, replacement electronic components, pump servicing, and optional service contracts to maintain stable baseline performance and dependable chromatographic reproducibility. Purchasing a certified refurbished Waters Alliance 2695 HPLC System with Waters 2414 Refractive Index Detector allows laboratories to significantly reduce capital expenditures while still benefiting from reliable chromatographic separation, stable RID performance, and proven long-term analytical reliability for routine and high-throughput laboratory applications.

ASTM D6591: Determination of Aromatic Hydrocarbon Types in Middle Distillates Using the Alliance Waters 2695 with Waters 2414 Refractive Index RI Detector

The Waters Alliance 2695 HPLC System with Waters 2414 Refractive Index Detector provides a reliable and effective platform for laboratories performing ASTM D6591 for the determination of aromatic hydrocarbon types in middle distillates. This configuration delivers stable chromatographic separation, reproducible retention times, and dependable refractive index detection for the analysis of monoaromatic, diaromatic, and polyaromatic hydrocarbon fractions commonly found in diesel fuels, jet fuels, and related petroleum products. The Waters Alliance 2695 HPLC platform offers precise solvent delivery, low carryover, and consistent gradient performance, while the 2414 RID provides stable baseline operation and sensitive detection for compounds that may exhibit limited UV absorbance characteristics. The system is well suited for refinery, petrochemical, and fuel testing laboratories requiring accurate hydrocarbon group-type analysis, efficient calibration workflows, and dependable long-term reproducibility for ASTM-compliant testing applications. Combined with reliable chromatographic performance, automated sample handling capabilities, and robust operational stability, the Waters Alliance 2695 HPLC System with 2414 RID delivers excellent analytical confidence and high-throughput performance for petroleum and fuel characterization workflows.

AMP Tech Analytical Solutions for Academic Research and Grant-Funded Laboratories

At AMPTIUS | AMP Tech Instruments, we support the advancement of scientific education and innovation by providing cost-effective analytical instruments tailored to the unique budget constraints of the academic sector. Every pre-owned system in our inventory is independently evaluated and fully verified within our in-house testing laboratory, making our AMP Tech Certified equipment an ideal choice for university chemistry departments, core facilities, and researchers optimizing limited grant funding. Because academic applications vary heavily from undergraduate teaching labs to complex graduate research, we precisely document each unique listing to ensure the specific components align with your educational goals or specific institutional SOPs. To guarantee that your system includes the exact module configuration required for your research methodology and to align with your university’s procurement process or funding timeline, we highly encourage you to connect directly with our active sales management team or request a customized quote before purchase.