Agilent Ultivo Triple Quad LC/MS/MS System with 1260 Infinity II Front End

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Agilent Ultivo Triple Quad LC/MS/MS System: Applications in Pharma, Food, and Environmental Labs

The Agilent Ultivo Triple Quadrupole LC/MS System with Agilent 1260 Infinity II HPLC System front end is widely used for high-sensitivity targeted quantitative analysis in pharmaceutical, environmental, food safety, clinical, forensic, biotechnology, and research laboratories. Common laboratory applications include pharmaceutical assay testing, impurity profiling, pharmacokinetic (PK) studies, bioavailability analysis, drug metabolism research, and biomarker quantitation in workflows aligned with USP, FDA, ICH, and cGMP analytical requirements. Environmental laboratories commonly utilize the system for PFAS analysis following EPA Methods 533 and 537.1, pesticide screening, pharmaceutical residue monitoring, perchlorate testing, and emerging contaminant analysis in water and soil samples. In food safety laboratories, the configuration supports multi-residue pesticide analysis, veterinary drug testing, mycotoxin quantitation, and food contaminant screening following AOAC analytical frameworks. Clinical and toxicology laboratories frequently apply the system for hormone analysis, therapeutic drug monitoring, drug screening, and toxicology workflows requiring ultra-low detection limits and reliable quantitative performance. The Ultivo Triple Quad LC/MS/MS platform utilizes advanced Multiple Reaction Monitoring (MRM) technology for exceptional sensitivity and selectivity, while the Agilent 1260 Infinity II front end delivers stable solvent delivery, low carryover, reliable chromatographic separation, and dependable retention time reproducibility for routine and high-throughput laboratory applications.

Agilent Ultivo Triple Quadrupole LC/MS System with Agilent 1260: Refurbished System Benefits and Pricing

The Agilent Ultivo Triple Quadrupole LC/MS System with Agilent 1260 Infinity II HPLC System front end provides a compact and high-performance LC-MS/MS solution for pharmaceutical, environmental, food safety, clinical, and research laboratories requiring ultra-sensitive quantitative analysis and high-throughput workflows. New systems typically range from approximately $280,000 to over $350,000, depending on ion source configuration, software packages, automation features, and compliance options, while certified refurbished systems generally range from $110,000 to $180,000, offering substantial savings on initial capital investment. In addition to acquisition costs, laboratories should consider ongoing operational expenses such as LC solvents, mobile phase additives, analytical columns, nitrogen gas generation or supply, vacuum pump maintenance, ion source cleaning, calibration standards, pump seals, tubing, preventive maintenance, software licensing, and compliance-related qualification support for USP, FDA, EPA, AOAC, ISO, and cGMP workflows. Long-term ownership considerations may also include detector servicing, autosampler maintenance, replacement electronic components, and optional service contracts to maintain stable chromatographic performance and dependable mass spectrometry sensitivity in high-throughput laboratory environments. Purchasing a certified refurbished Agilent Ultivo Triple Quad LC/MS/MS System with 1260 Infinity II Front End allows laboratories to significantly reduce ownership costs while still benefiting from exceptional MRM sensitivity, reliable chromatographic separation, compact system design, and proven long-term analytical performance for regulated and research-based laboratory applications.

EPA Method 1633A: Analysis of Per- and Polyfluoroalkyl Substances (PFAS) Using Agilent Ultivo Triple Quadrupole LC/MS System

The Agilent Ultivo Triple Quadrupole LC/MS System with Agilent 1260 Infinity II HPLC System front end provides a highly sensitive and reliable analytical platform for laboratories performing EPA Method 1633 for the analysis of per- and polyfluoroalkyl substances (PFAS) in environmental matrices. This LC-MS/MS configuration delivers excellent low-level detection capability, strong analytical selectivity, and dependable quantitative reproducibility for targeted PFAS compounds in water, wastewater, biosolids, soil, sediment, tissue, and landfill leachate samples. The Ultivo Triple Quad utilizes advanced Multiple Reaction Monitoring (MRM) technology to support trace-level PFAS quantitation with reduced background interference and high analytical confidence, while the Agilent 1260 Infinity II front end provides stable solvent delivery, low carryover, and reproducible chromatographic separation critical for regulated PFAS workflows. The compact system design, automated workflow compatibility, and robust ionization performance make the platform well suited for high-throughput environmental laboratories requiring reliable compliance support and efficient sample analysis. Combined with dependable retention time stability, sensitive PFAS detection, and long-term operational reliability, the Agilent Ultivo Triple Quad LC/MS/MS System with 1260 Infinity II Front End provides laboratories with exceptional performance for EPA Method 1633 PFAS testing applications.