Waters Xevo TQ-S Micro Triple Quadrupole LC-MS/MS with Acquity I Class Front End

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Waters Xevo TQ-S Micro Triple Quadrupole LC-MS/MS with Acquity I Class Front End: Applications in Pharma, Food, and Environmental Labs

The Waters Xevo TQ-S Micro Triple Quadrupole Mass Spectrometer with a Waters ACQUITY UPLC I-Class System front end is a high-performance LC-MS/MS platform widely used in environmental, pharmaceutical, food safety, clinical research, biotechnology, forensic, toxicology, and academic laboratories for targeted quantitative analysis. Common laboratory applications include PFAS analysis, pesticide residue testing, pharmaceutical bioanalysis, therapeutic drug monitoring, veterinary drug residue screening, mycotoxin detection, environmental contaminant monitoring, biomarker quantification, metabolomics research, forensic toxicology investigations, and food safety compliance testing. The Xevo TQ-S Micro delivers exceptional sensitivity and selectivity through Multiple Reaction Monitoring (MRM), enabling reliable quantitation of trace-level compounds in complex sample matrices while maintaining a broad dynamic range and excellent reproducibility. The ACQUITY I-Class front end provides ultra-high-performance chromatographic separations, low dispersion fluidics, and precise solvent delivery, supporting rapid analyses and high sample throughput. Environmental laboratories frequently utilize this configuration for PFAS, pesticide, and emerging contaminant testing, while pharmaceutical and biotechnology laboratories rely on it for pharmacokinetic studies, drug metabolism research, and clinical assay development. Food safety laboratories benefit from simultaneous screening and quantitation of contaminants across diverse sample types. Combined with advanced LC-MS/MS sensitivity, robust UPLC performance, dependable quantitative accuracy, and proven Waters reliability, the Waters Xevo TQ-S Micro Triple Quadrupole LC-MS/MS with ACQUITY I-Class Front End provides a powerful solution for demanding trace-level analytical applications requiring regulatory-grade performance and high-throughput operation.

Waters Xevo TQ-S Micro Triple Quadrupole LC-MS/MS: Refurbished System Benefits and Pricing

Certified refurbished systems typically range from approximately $100,000 to $125,000, offering substantial savings compared to new systems, which commonly range from approximately $300,000 to $365,000 depending on configuration, software packages, and application-specific options. Beyond the initial acquisition cost, laboratories should budget for ongoing operational expenses, including UPLC columns, solvents, calibration standards, sample preparation supplies, nitrogen gas generation or supply, pump seals, autosampler consumables, ion source maintenance, vacuum pump servicing, replacement ion optics, software support, preventive maintenance, and compliance-related qualification services. Long-term ownership considerations may also include detector maintenance, performance verification, service agreements, and routine system optimization to ensure consistent analytical performance and regulatory compliance. Purchasing a certified refurbished Waters Xevo TQ-S Micro Triple Quadrupole LC-MS/MS with ACQUITY I-Class Front End allows laboratories to significantly reduce capital expenditures while maintaining access to exceptional MRM sensitivity, robust quantitative accuracy, high-throughput UPLC separations, and proven analytical performance for applications such as PFAS testing, pesticide residue analysis, pharmaceutical bioanalysis, mycotoxin screening, environmental monitoring, food safety compliance, and targeted contaminant quantification.

EPA Method 1633: Analysis of Per- and Polyfluoroalkyl Substances (PFAS) Using the Waters Xevo TQ-S Micro Triple Quadrupole LC-MS/MS

The Waters Xevo TQ-S Micro Triple Quadrupole Mass Spectrometer with an Waters ACQUITY UPLC I-Class System front end provides a highly effective platform for EPA Method 1633, which is used for the determination of per- and polyfluoroalkyl substances (PFAS) in environmental matrices including wastewater, surface water, groundwater, soil, sediment, biosolids, and tissue samples. The ACQUITY I-Class UPLC delivers exceptional chromatographic resolution, precise solvent delivery, and high-throughput separations that are critical for resolving complex PFAS analyte panels. The Xevo TQ-S Micro offers outstanding sensitivity and selectivity through Multiple Reaction Monitoring (MRM), enabling accurate quantitation of target PFAS compounds at trace and ultra-trace concentration levels while minimizing matrix interferences. Environmental laboratories benefit from robust isotope dilution quantitation, broad dynamic range, excellent reproducibility, and reliable detection of both legacy and emerging PFAS compounds across challenging sample matrices. The system's high sensitivity supports stringent reporting requirements and data quality objectives associated with modern PFAS monitoring programs, remediation projects, and regulatory compliance initiatives. Combined with advanced UPLC performance, highly sensitive triple quadrupole mass spectrometry, and proven Waters reliability, the Waters Xevo TQ-S Micro LC-MS/MS with ACQUITY I-Class Front End provides a powerful solution for EPA Method 1633 PFAS analysis and environmental contaminant monitoring applications.