Waters Acquity UPLC System w/ Binary SM SM FLR Detector

Insights by AMPTIUS | AMP Tech Instruments

Price and cost of ownership of Waters Acquity UPLC System w/ Binary SM SM FLR Detector

The Waters Acquity UPLC System with Binary Solvent Manager (SM), Sample Manager (SM), and Fluorescence (FLR) Detector is a high-performance ultra-performance liquid chromatography system designed for fast, high-resolution separations and exceptional sensitivity. A new system is priced at approximately $92,000, while a refurbished unit can be acquired for around $20,000, offering significant savings for labs focused on high-throughput analytical work. The Binary Solvent Manager provides rapid and accurate solvent delivery for consistent gradient performance, while the Sample Manager ensures precise sample injection and high reproducibility. The FLR Detector enhances detection of trace-level analytes, making the system ideal for pharmaceutical, food safety, environmental, and biomolecular applications requiring low detection limits. Operating costs include consumables such as UPLC columns, vials, solvents, lamp replacements (for detectors), and maintenance on the pump seals and injector components. Software licensing and occasional hardware servicing, especially for the detector or autosampler, are also factors in long-term ownership. For labs seeking top-tier performance at a fraction of the original cost, a refurbished Waters Acquity UPLC system is a highly economical choice—particularly when purchased from a reputable source that offers system validation and a service warranty.

Waters ACQUITY UPLC with FLR Detector – Ideal for AOAC, and other Fluorescence-Based Methods

The Waters ACQUITY UPLC System with Binary Solvent Manager, Sample Manager, and FLR Detector is designed for high-sensitivity analysis requiring precise separation and low detection limits. It is widely used in pharmaceutical, food, environmental, and clinical laboratories for applications such as impurity profiling, trace-level detection of fluorescent or derivatized compounds, and monitoring of biomarkers, pollutants, and pesticides. Its fast analysis speed and enhanced fluorescence detection make it suitable for routine testing and research workflows involving mycotoxins, amino acids, vitamins, PAHs, and flavonoids. This system supports a variety of regulatory and validated methods that require fluorescence detection. It is compatible with selected AOAC Official Methods that utilize post-column or pre-column derivatization to enable fluorescence detection of specific food additives and contaminants. The system also supports workflows for glyphosate analysis in drinking water using post-column derivatization and fluorescence, as required by certain regulatory or vendor-adapted methods. Its sensitivity, speed, and reproducibility make it a dependable solution for high-throughput laboratories working under strict compliance standards.