Waters Acquity UPLC System with Binary SM SM FLR Detector

Insights by AMPTIUS | AMP Tech Instruments

Price and cost of ownership of Waters Acquity UPLC System with Binary SM SM FLR Detector

Investing in the Waters ACQUITY UPLC System with Binary Solvent Manager, Sample Manager, and Fluorescence Detector (FLR) provides laboratories with a high-sensitivity, high-throughput platform for advanced chromatographic analysis. A new system is typically priced around $92,000, while a certified refurbished unit averages approximately $20,000, offering substantial cost savings without compromising performance. The Binary Solvent Manager ensures precise gradient delivery, the Sample Manager enables accurate and reproducible injections, and the FLR detector delivers exceptional sensitivity for trace-level analytes in pharmaceutical, environmental, food safety, and biomolecular applications. Ongoing costs include consumables such as UPLC columns, vials, solvents, and lamp replacements, along with maintenance of pump seals and injector components. Additional considerations include software licensing and periodic servicing of key modules. A refurbished system with validated performance and warranty offers a cost-effective path to achieving top-tier UPLC capabilities while maintaining long-term budget efficiency.

Waters ACQUITY UPLC with FLR Detector – Ideal for AOAC, and other Fluorescence-Based Methods

The Waters ACQUITY UPLC System with Binary Solvent Manager, Sample Manager, and Fluorescence Detector (FLR) is designed for high-sensitivity analysis requiring precise separations and low detection limits across pharmaceutical, food, environmental, and clinical laboratories. It is widely used for impurity profiling and trace-level detection of fluorescent or derivatized compounds, including mycotoxins, amino acids, vitamins, PAHs, flavonoids, pesticides, and environmental pollutants, while also supporting biomarker monitoring in research settings. Its fast analysis speed and enhanced fluorescence detection make it ideal for both routine testing and advanced workflows. This configuration supports validated methods such as select AOAC Official Methods that utilize fluorescence detection through derivatization, as well as glyphosate analysis workflows using post-column derivatization and fluorescence-based detection. With its precision, reproducibility, and high-throughput capability, this system provides a dependable solution for laboratories operating under strict regulatory and analytical performance requirements.