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SCIEX 4500 Triple Quad LC/MS/MS System | Shimadzu XR HPLC & Workstation

$150,000.00

Fully Tested and Refurbished

Warranty: Includes a 90-Day warranty

International Shipping: Shipping to Anywhere in the World for International Orders



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PRODUCT INFORMATION
Additional Information
PRODUCT INFORMATION

This refrubished SCIEX 4500 Triple Quad LC/MS/MS System with Shimadzu XR HPLC and workstation was acquired by our team in excellent working condition. The system was acquired from a working environment and was operating as intended. Upon arrival the system underwent a comprehensive inspection by our in-house laboratory technicians. 

The system is offered as a fully Operational and Performance Qualification (OP/OQ) tested and was lightly refurbished in our on-site certification lab (The system is in excellent condition so little to no refurbishing was necessary). After successfully passing all validation protocols, this SCIEX 4500 system is offered as AMPTIUS Certified, Warrantied  and fully ready to meet the demands of your laboratory.

This SCIEX 4500 Triple Quadrupole LC/MS/MS system is fully equipped for high-performance liquid chromatography–mass spectrometry applications. It features the robust Turbo V™ ion source (ESI) for enhanced ionization efficiency and sensitivity. Paired with a Shimadzu XR HPLC system, the configuration includes a SIL-20AC HT thermostatted autosampler, dual LC-20AD XR binary high-pressure pumps, a DGU-20A in-line degasser, and a CTO-20AC column oven, ensuring accurate solvent delivery and stable temperature control across your workflow.

The system also comes complete with a vacuum pump specifically configured for the SCIEX 4500 platform and a pre-configured computer workstation running SCIEX Analyst software, ready for immediate operation. All essential accessories are included, such as LC-MS interface tubing, source cables, and power cords. Optional upgrades, such as a nitrogen generator and uninterruptible power supply (UPS)—are available to support continuous operation and protect against workflow disruptions.

At AMPTIUS | AMP Tech Instruments, we specialize in professionally refurbished analytical instruments that offer proven performance at a fraction of the cost of new systems. Every instrument we sell, including this SCIEX 4500 Triple Quad LC/MS/MS System, is rigorously tested, expertly refurbished using OEM components, and certified in-house to meet demanding operational standards. Whether you’re expanding your capabilities or replacing aging equipment, our certified systems are ready to support your lab’s success. Contact Amptius today to request a quote or consultation—your next dependable instrument is just a message away.

Included with SCIEX 4500 Triple Quad LC/MS/MS System | Shimadzu XR HPLC & Workstation

  • MASS SPECTROMETER:
  • SCIEX 4500 Triple Quadrupole LC/MS/MS System
  • Equipped with Turbo V™ Ion Source (ESI)
  • SHIMADZU LC SYSTEM:
  • SIL-20AC HT Thermostatted Autosampler
  • LC-20AD XR Binary High-Pressure Pumps (x2)
  • DGU-20A In-line Degasser
  • CTO-20AC Column Oven
  • SUPPORTING HARDWARE:
  • Vacuum Pump (configured for SCIEX 4500 system)
  • Pre-configured Computer Workstation with installed operating software (SCIEX Analyst)
  • All necessary LC-MS interface tubing, source cables, and power cords
  • WARRANTY:
  • 90-Days
  • OPTIONAL ADD-ONS:
  • Nitrogen Generator
  • Uninterruptible Power Supply (UPS)
  • Additional Warranty

Disclaimer: Unless otherwise stated the seller is not authorized by or associated with the original equipment manufacturer. This product has not been reviewed by the manufacturer to reverify its quality or compatibility with its other products.

Additional Information

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Price and cost of ownership of SCIEX 4500 Triple Quad LC/MS/MS System | Shimadzu XR HPLC & Workstation

Investing in the SCIEX 4500 Triple Quad LC/MS/MS System paired with Shimadzu XR HPLC and workstation is a significant decision for laboratories requiring high-throughput, quantitative mass spectrometry performance. A new system costs approximately $480,000, while a certified refurbished unit averages around $160,000, offering a substantial reduction in capital investment without compromising analytical capabilities. The SCIEX 4500 builds on the legacy of the API 4000 series, delivering enhanced sensitivity, precision, and ruggedness across demanding applications such as pharmaceutical bioanalysis, food safety testing, clinical research, and environmental monitoring. The Shimadzu XR HPLC provides ultra-fast, high-resolution chromatographic separation, complementing the mass spectrometer’s ability to deliver rapid, reliable quantitative results. The system is well-suited for MRM-based workflows where sensitivity and specificity are critical. A certified refurbished SCIEX 4500 LC-MS/MS system undergoes thorough requalification and calibration, often including a warranty and technical support, making it a cost-effective solution for labs needing advanced mass spectrometry on a constrained budget. For organizations looking to expand their analytical capabilities while controlling costs, a refurbished 4500 system with Shimadzu XR HPLC is a smart and scientifically sound investment.


SCIEX 4500 LC MS MS MS for Environmental, Pesticide, PFAS, Pharma & More

SCIEX is a globally recognized leader in mass spectrometry and analytical instrumentation, renowned for its innovation, precision, and dependability in quantitative analysis. With decades of experience across pharmaceutical, environmental, food safety, and clinical research sectors, SCIEX has earned a reputation for producing high-performance LC-MS/MS systems that deliver reliable, reproducible results. Their dedication to scientific advancement and technical support makes SCIEX a trusted name in analytical laboratories worldwide.


Who's using SCIEX 4500 Triple Quad LCMS Systems

A study at the University of Florida used the SCIEX 4500 to quantify pharmaceuticals in reclaimed water, highlighting its sensitivity for low-ppb detection. Research from Wageningen University used the SCIEX 4500 with Shimadzu HPLC to analyze multi-class pesticides in produce and mycotoxins in grains with high throughput. A study by the University of Toronto used the 4500 system to measure opioid concentrations in plasma to study metabolism rates and guide personalized medicine protocols.