Agilent 7-Piece 1100 HPLC System with FLD and QuatPump

Insights by AMPTIUS | AMP Tech Instruments

Agilent 1100 HPLC with FLD and QuatPump: Applications in Pharma, Food, and Environmental Labs

The Agilent 1100 HPLC System, configured with a Fluorescence Detector (FLD), Quaternary Pump, autosampler, column compartment, degasser, and chromatography workstation, is a highly sensitive liquid chromatography platform widely used in environmental, pharmaceutical, food safety, biotechnology, chemical, and academic laboratories. Common laboratory applications include polycyclic aromatic hydrocarbon (PAH) analysis, mycotoxin testing, aflatoxin quantification, amino acid analysis, pharmaceutical impurity profiling, pesticide residue analysis following derivatization, biomarker research, and trace-level contaminant monitoring. The Fluorescence Detector provides exceptional sensitivity and selectivity for naturally fluorescent compounds and analytes that can be derivatized for fluorescence detection, making it ideal for low-level quantitation in complex sample matrices. The Quaternary Pump supports flexible mobile phase blending and gradient development, allowing laboratories to optimize separations across a wide range of analytical methods. Environmental laboratories frequently utilize this configuration for PAH analysis and drinking water testing, while food safety laboratories rely on it for mycotoxin screening and contaminant monitoring. Combined with proven Agilent reliability, robust chromatographic performance, excellent quantitative accuracy, and highly sensitive fluorescence detection, the Agilent 1100 HPLC System with FLD and Quaternary Pump remains a trusted solution for demanding trace-level analytical applications.

Agilent 1100 HPLC with FLD and QuatPump: Refurbished System Benefits and Pricing

The Agilent 1100 HPLC System with a Fluorescence Detector (FLD) and Quaternary Pump provides an economical and highly sensitive liquid chromatography solution for environmental, food safety, pharmaceutical, biotechnology, and research laboratories. Certified refurbished systems typically range from approximately $12,000 to $14,500, offering substantial savings compared to comparable new systems such as an Agilent 1260 Infinity II Prime LC equipped with an InfinityLab FLD and Quaternary Flex Pump, which commonly range from approximately $42,000 to $51,000 or more, depending on configuration and software options. Beyond the initial acquisition cost, laboratories should account for ongoing operational expenses, including HPLC columns, solvents, mobile phase preparation, pump seals, check valves, autosampler maintenance, fluorescence lamp replacement, calibration standards, software support, preventive maintenance, and compliance-related qualification services. Long-term ownership costs remain manageable due to the proven reliability of the Agilent 1100 platform, widespread availability of replacement parts, and straightforward serviceability. Purchasing a certified refurbished Agilent 1100 HPLC with FLD and Quaternary Pump allows laboratories to significantly reduce capital expenditures while benefiting from highly sensitive fluorescence detection, flexible method development capabilities, dependable chromatographic performance, and proven analytical reliability for applications such as PAH analysis, mycotoxin testing, pharmaceutical impurity analysis, amino acid determination, and trace-level contaminant monitoring.

EPA Method 547: Determination of Glyphosate in Drinking Water Using Agilent 1100 HPLC with FLD and QuatPump

The Agilent 1100 HPLC System with a Fluorescence Detector (FLD) and Quaternary Pump is well-suited for EPA Method 547, which determines glyphosate and related aminophosphonic acid compounds in drinking water following post-column derivatization and fluorescence detection. The highly sensitive FLD provides the low-level detection capability required for trace analysis of derivatized glyphosate, while the Agilent 1100 platform delivers reliable chromatographic performance and reproducible retention times necessary for regulatory drinking water monitoring. The Quaternary Pump supports precise mobile phase blending and stable flow control, which are critical for maintaining consistent post-column reaction conditions and analytical accuracy. Laboratories benefit from dependable quantitation, excellent method reproducibility, and robust long-term performance when analyzing challenging water matrices. The system's proven reliability, ease of maintenance, and widespread use in environmental testing laboratories make it an effective solution for routine compliance monitoring, water quality assessments, and regulatory testing programs. Combined with sensitive fluorescence detection and stable chromatographic operation, the Agilent 1100 HPLC with FLD and Quaternary Pump provides a trusted platform for EPA Method 547 glyphosate analysis in drinking water applications.